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Measles virus attachment proteins with impaired ability to bind CD46 interact more efficiently with the homologous fusion protein

Fusion promotion by measles virus (MV) depends on an interaction between the hemagglutinin (H) and fusion (F) glycoproteins. Amino acid substitutions in MV H that drastically reduce hemagglutinating activity result in an increase in the amount of H (primarily the 74 kDa isoform) detectable in a comp...

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Detalhes bibliográficos
Main Authors: Corey, Elizabeth A., Iorio, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650383/
https://ncbi.nlm.nih.gov/pubmed/19013625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.10.018
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