Multiple Amino Acid Substitutions in Hemagglutinin Are Necessary for Wild-Type Measles Virus To Acquire the Ability To Use Receptor CD46 Efficiently

Measles virus (MV) possesses two envelope glycoproteins, namely, the receptor-binding hemagglutinin (H) and fusion proteins. Wild-type MV strains isolated in B-lymphoid cell lines use signaling lymphocyte activation molecule (SLAM), but not CD46, as a cellular receptor, whereas MV vaccine strains of...

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Bibliographic Details
Main Authors: Tahara, Maino, Takeda, Makoto, Seki, Fumio, Hashiguchi, Takao, Yanagi, Yusuke
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865989/
https://ncbi.nlm.nih.gov/pubmed/17182683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02449-06
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