Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes

Human leukocyte antigen (HLA) class I molecules present a variety of posttranslationally modified epitopes at the cell surface, although the consequences of such presentation remain largely unclear. Phosphorylation plays a critical cellular role, and deregulation in phosphate metabolism is associate...

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Detalhes bibliográficos
Main Authors: Petersen, Jan, Wurzbacher, Stephanie J., Williamson, Nicholas A., Ramarathinam, Sri H., Reid, Hugh H., Nair, Ashish K. N., Zhao, Anne Y., Nastovska, Roza, Rudge, Geordie, Rossjohn, Jamie, Purcell, Anthony W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650342/
https://ncbi.nlm.nih.gov/pubmed/19196958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812901106
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