A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci

There is considerable variability in the susceptibility of smokers to develop chronic obstructive pulmonary disease (COPD). The only known genetic risk factor is severe deficiency of α(1)-antitrypsin, which is present in 1–2% of individuals with COPD. We conducted a genome-wide association study (GW...

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Detaylı Bibliyografya
Asıl Yazarlar: Pillai, Sreekumar G., Ge, Dongliang, Zhu, Guohua, Kong, Xiangyang, Shianna, Kevin V., Need, Anna C., Feng, Sheng, Hersh, Craig P., Bakke, Per, Gulsvik, Amund, Ruppert, Andreas, Lødrup Carlsen, Karin C., Roses, Allen, Anderson, Wayne, Rennard, Stephen I., Lomas, David A., Silverman, Edwin K., Goldstein, David B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2009
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650282/
https://ncbi.nlm.nih.gov/pubmed/19300482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000421
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