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Brevetoxin activation of voltage-gated sodium channels regulates Ca(2+) dynamics and ERK1/2 phosphorylation in murine neocortical neurons
Voltage-gated sodium channels (VGSC) are involved in the generation of action potentials in neurons. Brevetoxins (PbTx) are potent allosteric enhancers of VGSC function and are associated with the periodic ‘red tide’ blooms. Using PbTx-2 as a probe, we have characterized the effects of activation of...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650275/ https://ncbi.nlm.nih.gov/pubmed/15086530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2004.02407.x |
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