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Neurosteroids in the context of stress: Implications for depressive disorders
Animal models indicate that the neuroactive steroids 3α,5α-THP (allopregnanolone) and 3α,5α-THDOC (allotetrahydroDOC) are stress responsive, serving as homeostatic mechanisms in restoring normal GABAergic and hypothalamic-pituitary-adrenal (HPA) function following stress. While neurosteroid increase...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650267/ https://ncbi.nlm.nih.gov/pubmed/17597217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2007.05.006 |
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