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Hypothyroidism in transgenic mice expressing IFN-γ in the thyroid

IFN-γ has been implicated with contradictory results in the pathogenetic process of autoimmune (Hashimoto's) thyroiditis, the most common cause of hypothyroidism in adults. To test whether the local production of IFN-γ can lead to thyroid dysfunction, we have generated transgenic mice that express c...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Caturegli, P., Hejazi, M., Suzuki, K., Dohan, O., Carrasco, N., Kohn, L. D., Rose, N. R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2000
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26502/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10677524/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.020522597
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