Restoration of IFNγR subunit assembly, IFNγ signaling and parasite clearance in Leishmania donovani infected macrophages: role of membrane cholesterol.

Despite the presence of significant levels of systemic Interferon gamma (IFNγ), the host protective cytokine, Kala-azar patients display high parasite load with downregulated IFNγ signaling in Leishmania donovani (LD) infected macrophages (LD-MØs); the cause of such aberrant phenomenon is unknown. H...

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Detalhes bibliográficos

Principais autores:	Subha Sen, Koushik Roy, Sandip Mukherjee, Rupkatha Mukhopadhyay, Syamal Roy
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2011-09-01
coleção:	PLoS Pathogens
Acesso em linha:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002229&type=printable
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