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miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination

Duplication of the gene encoding lamin B1 (LMNB1) with increased mRNA and protein levels has been shown to cause severe myelin loss in the brains of adult-onset autosomal dominant leukodystrophy patients. Similar to many neurodegenerative disorders, patients with adult-onset autosomal dominant leuko...

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Bibliografske podrobnosti
Main Authors: Lin, Shu-Ting, Fu, Ying-Hui
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Limited 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650193/
https://ncbi.nlm.nih.gov/pubmed/19259393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.001065
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