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β(2)-Adrenoceptor signaling is required for the development of an asthma phenotype in a murine model
Chronic regular use of β(2)-adrenoceptor (β(2)-AR) agonists in asthma is associated with a loss of disease control and increased risk of death. Conversely, we have found that administration of β(2)-AR inverse agonists results in attenuation of the asthma phenotype in an allergen-driven murine model....
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650174/ https://ncbi.nlm.nih.gov/pubmed/19171883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810902106 |
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