Cross-presenting human γδ T cells induce robust CD8(+) αβ T cell responses

γδ T cells are implicated in host defense against microbes and tumors but their mode of function remains largely unresolved. Here, we have investigated the ability of activated human Vγ9Vδ2(+) T cells (termed γδ T-APCs) to cross-present microbial and tumor antigens to CD8(+) αβ T cells. Although thi...

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Bibliografiska uppgifter
Huvudupphovsmän: Brandes, Marlène, Willimann, Katharina, Bioley, Gilles, Lévy, Nicole, Eberl, Matthias, Luo, Ming, Tampé, Robert, Lévy, Frédéric, Romero, Pedro, Moser, Bernhard
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650152/
https://ncbi.nlm.nih.gov/pubmed/19171897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810059106
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