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Prolonged antigen survival and cytosolic export in cross-presenting human γδ T cells

Human blood Vγ9Vδ2 T cells respond to signals from microbes and tumors and subsequently differentiate into professional antigen-presenting cells (γδ T-APCs) for induction of CD4(+) and CD8(+) T cell responses. γδ T-APCs readily take up and degrade exogenous soluble protein for peptide loading on MHC...

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Detalhes bibliográficos
Main Authors: Meuter, Simone, Eberl, Matthias, Moser, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889313/
https://ncbi.nlm.nih.gov/pubmed/20413723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002769107
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