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Brief heat treatment increases cytotoxicity of Mannheimia haemolytica leukotoxin in an LFA-1 independent manner
Mannheimia haemolytica is an important respiratory pathogen in cattle. Its predominant virulence factor is a leukotoxin (LKT) that is a member of the RTX family of exotoxins produced by a variety of gram negative bacteria. LKT binds to the CD18 chain of β2 integrins on bovine leukocytes, resulting i...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2649972/ https://ncbi.nlm.nih.gov/pubmed/19185607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micpath.2008.12.002 |
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