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EGF receptor signaling blocks aryl hydrocarbon receptor-mediated transcription and cell differentiation in human epidermal keratinocytes

Dioxin is an extremely potent carcinogen. In highly exposed people, the most commonly observed toxicity is chloracne, a pathological response of the skin. Most of the effects of dioxin are attributed to its activation of the aryl hydrocarbon receptor (AHR), a transcription factor that binds to the A...

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מידע ביבליוגרפי
Main Authors: Sutter, Carrie Hayes, Yin, Hong, Li, Yunbo, Mammen, Jennifer S., Bodreddigari, Sridevi, Stevens, Gaylene, Cole, Judith A., Sutter, Thomas R.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649958/
https://ncbi.nlm.nih.gov/pubmed/19255421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900874106
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