Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1β in human monocytes and multiple sclerosis

Mechanisms of action as well as cellular targets of glatiramer acetate (GA) in multiple sclerosis (MS) are still not entirely understood. IL-1β is present in CNS-infiltrating macrophages and microglial cells and is an important mediator of inflammation in experimental autoimmune encephalitis (EAE),...

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Détails bibliographiques
Auteurs principaux: Burger, Danielle, Molnarfi, Nicolas, Weber, Martin S., Brandt, Karim J., Benkhoucha, Mahdia, Gruaz, Lyssia, Chofflon, Michel, Zamvil, Scott S., Lalive, Patrice H.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649955/
https://ncbi.nlm.nih.gov/pubmed/19255448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812183106
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