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Maternal celiac disease autoantibodies bind directly to syncytiotrophoblast and inhibit placental tissue transglutaminase activity

BACKGROUND: Celiac disease (CD) occurs in as many as 1 in 80 pregnant women and is associated with poor pregnancy outcome, but it is not known if this is an effect on maternal nutrient absorption or, alternatively, if the placenta is an autoimmune target. The major autoantigen, tissue transglutamina...

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Detalhes bibliográficos
Main Authors: Anjum, Naheed, Baker, Philip N, Robinson, Nicola J, Aplin, John D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649929/
https://ncbi.nlm.nih.gov/pubmed/19228395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-7-16
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