Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10)

We identified a viral IL-10 homolog encoded by an ORF (UL111a) within the human cytomegalovirus (CMV) genome, which we designated cmvIL-10. cmvIL-10 can bind to the human IL-10 receptor and can compete with human IL-10 for binding sites, despite the fact that these two proteins are only 27% identica...

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Bibliografiske detaljer
Main Authors: Kotenko, Sergei V., Saccani, Simona, Izotova, Lara S., Mirochnitchenko, Olga V., Pestka, Sidney
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC26498/
https://ncbi.nlm.nih.gov/pubmed/10677520
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