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Structural Features and Reactivity of (sparteine)PdCl(2): A Model for Selectivity in the Oxidative Kinetic Resolution of Secondary Alcohols

The chiral ligand (−)-sparteine and PdCl(2) catalyze the enantioselective oxidation of secondary alcohols to ketones and thus effect a kinetic resolution. The structural features of sparteine that led to the selectivity observed in the reaction were not clear. Substitution experiments with pyridine...

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Detalhes bibliográficos
Main Authors: Trend, Raissa M., Stoltz, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649720/
https://ncbi.nlm.nih.gov/pubmed/18975867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja804955e
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