Načítá se...
Allosteric Effects on Substrate Dissociation from Cytochrome P450 3A4 in Nanodiscs Observed by Ensemble and Single-Molecule Fluorescence Spectroscopy
[Image: see text] Cytochrome P450 3A4 is a major human drug-metabolizing enzyme, and displays pharmacologically-relevant allosteric kinetics caused by multiple substrate and/or effector binding. Here, in the first single-molecule fluorescence studies of CYPs, we use total internal reflection fluores...
Uloženo v:
| Hlavní autoři: | , , , |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2649694/ https://ncbi.nlm.nih.gov/pubmed/18980315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja805772r |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|