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The Role of FilGAP-Filamin A Interactions in Mechanoprotection

Cells in mechanically active environments are subjected to high-amplitude exogenous forces that can lead to cell death. Filamin A (FLNa) may protect cells from mechanically induced death by mechanisms that are not yet defined. We found that mechanical forces applied through integrins enhanced Rac-me...

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Autors principals: Shifrin, Yulia, Arora, Pamela D., Ohta, Yasutaka, Calderwood, David A., McCulloch, Christopher A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649276/
https://ncbi.nlm.nih.gov/pubmed/19144823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-08-0872
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