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Roles of BLOC-1 and Adaptor Protein-3 Complexes in Cargo Sorting to Synaptic Vesicles

Neuronal lysosomes and their biogenesis mechanisms are primarily thought to clear metabolites and proteins whose abnormal accumulation leads to neurodegenerative disease pathology. However, it remains unknown whether lysosomal sorting mechanisms regulate the levels of membrane proteins within synapt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Newell-Litwa, Karen, Salazar, Gloria, Smith, Yoland, Faundez, Victor
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649275/
https://ncbi.nlm.nih.gov/pubmed/19144828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-05-0456
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