The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapse

Dysbindin assembles into the biogenesis of lysosome-related organelles complex 1 (BLOC-1), which interacts with the adaptor protein complex 3 (AP-3), mediating a common endosome-trafficking route. Deficiencies in AP-3 and BLOC-1 affect synaptic vesicle composition. However, whether AP-3-BLOC-1–depen...

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Detalhes bibliográficos
Main Authors: Larimore, Jennifer, Tornieri, Karine, Ryder, Pearl V., Gokhale, Avanti, Zlatic, Stephanie A., Craige, Branch, Lee, Joshua D., Talbot, Konrad, Pare, Jean-Francois, Smith, Yoland, Faundez, Victor
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237628/
https://ncbi.nlm.nih.gov/pubmed/21998198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-07-0592
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