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Cleavage of Bacteriophage λ cI Repressor Involves the RecA C-terminal Domain

The SOS response to DNA damage in E. coli involves at least 43 genes, all under the control of the LexA repressor. Activation of these genes occurs when the LexA repressor cleaves itself, a reaction catalyzed by an active, extended RecA filament formed on DNA. It has been shown that the LexA repress...

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Main Authors: Galkin, Vitold E., Yu, Xiong, Bielnicki, Jakub, Ndjonka, Dieudonné, Bell, Charles E., Egelman, Edward H.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648975/
https://ncbi.nlm.nih.gov/pubmed/19013467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.10.081
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