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Structure of a Hyper-cleavable Monomeric Fragment of Phage λ Repressor Containing the Cleavage Site Region

The key event in the switch from lysogenic to lytic growth of phage lambda is the self-cleavage of lambda repressor, which is induced by the formation of a RecA-ssDNA-ATP filament at a site of DNA damage. Lambda repressor cleaves itself at the peptide bond between Ala111 and Gly112, but only when bo...

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Main Authors: Ndjonka, Dieudonné, Bell, Charles E.
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1896146/
https://ncbi.nlm.nih.gov/pubmed/16934834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.07.026
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