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Histone H2AX phosphorylation in response to changes in chromatin structure induced by altered osmolarity
DNA strand breaks trigger marked phosphorylation of histone H2AX (i.e. γ-H2AX). While DNA double-strand breaks (DSBs) provide a strong stimulus for this event, the accompanying structural alterations in chromatin may represent the actual signal that elicits γ-H2AX. Our data show that changes in chro...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2648872/ https://ncbi.nlm.nih.gov/pubmed/19064695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gen064 |
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