Histone H2AX phosphorylation in response to changes in chromatin structure induced by altered osmolarity

DNA strand breaks trigger marked phosphorylation of histone H2AX (i.e. γ-H2AX). While DNA double-strand breaks (DSBs) provide a strong stimulus for this event, the accompanying structural alterations in chromatin may represent the actual signal that elicits γ-H2AX. Our data show that changes in chro...

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Main Authors: Baure, Jennifer, Izadi, Atefeh, Suarez, Vannina, Giedzinski, Erich, Cleaver, James E., Fike, John R., Limoli, Charles L.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2009
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648872/
https://ncbi.nlm.nih.gov/pubmed/19064695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/gen064
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