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Promoter Methylation Blocks FES Protein-tyrosine Kinase Gene Expression in Colorectal Cancer

The FES locus encodes a unique non-receptor protein-tyrosine kinase (FES) traditionally viewed as a proto-oncogene but more recently implicated as a tumor suppressor in colorectal cancer (CRC). Recent studies have demonstrated that while FES is expressed in normal colonic epithelium, expression is l...

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Detalhes bibliográficos
Main Authors: Shaffer, Jonathan M., Smithgall, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648816/
https://ncbi.nlm.nih.gov/pubmed/19051325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20638
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