Mitochondrial H(2)O(2) emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

High dietary fat intake leads to insulin resistance in skeletal muscle, and this represents a major risk factor for type 2 diabetes and cardiovascular disease. Mitochondrial dysfunction and oxidative stress have been implicated in the disease process, but the underlying mechanisms are still unknown....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Anderson, Ethan J., Lustig, Mary E., Boyle, Kristen E., Woodlief, Tracey L., Kane, Daniel A., Lin, Chien-Te, Price, Jesse W., Kang, Li, Rabinovitch, Peter S., Szeto, Hazel H., Houmard, Joseph A., Cortright, Ronald N., Wasserman, David H., Neufer, P. Darrell
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2009
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648700/
https://ncbi.nlm.nih.gov/pubmed/19188683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37048
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