Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones

Phosphorylation is essential for the SR family of splicing factors/regulators to function in constitutive and regulated pre-mRNA splicing; yet both hypo- and hyperphosphorylation of SR proteins are known to inhibit splicing, indicating that SR protein phosphorylation must be tightly regulated in the...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Zhong, Xiang-Yang, Ding, Jian-Hua, Adams, Joseph A., Ghosh, Gourisankar, Fu, Xiang-Dong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2009
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648651/
https://ncbi.nlm.nih.gov/pubmed/19240134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1752109
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