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N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma

Studying the early stages of cancer can provide important insight into the molecular basis of the disease. We identified a preneoplastic stage in the patched (ptc) mutant mouse, a model for the brain tumor medulloblastoma. Preneoplastic cells (PNCs) are found in most ptc mutants during early adultho...

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Detalhes bibliográficos
Main Authors: Kessler, Jessica D., Hasegawa, Hiroshi, Brun, Sonja N., Yang, Zeng-Jie, Dutton, John W., Wang, Fan, Wechsler-Reya, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648542/
https://ncbi.nlm.nih.gov/pubmed/19171780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1759909
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