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Synthesis of Potential Early-Stage Intermediates in the Biosynthesis of FR900482 and Mitomycin C

[Image: see text] Beyond the identification of 3-amino-5-hydroxybenzoic acid (AHBA) and d-glucosamine as biosynthetic precursors to mitomycin C (5) and FR900482 (6), little is known about the pathway Nature uses to prepare these antitumor antibiotics. To gain some insight into their biosynthesis, am...

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Bibliografski detalji
Glavni autori: Chamberland, Stephen, Grüschow, Sabine, Sherman, David H., Williams, Robert M.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647965/
https://ncbi.nlm.nih.gov/pubmed/19161340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol802631c
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