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The Effect of Mutation of Carboxyl Side-Chain Amino Acids Near the Heme on the Midpoint Potentials and Ligand Binding Constants of Nitrophorin 2 and Its NO, Histamine and Imidazole Complexes

Nitrophorins (NPs) are a group of NO-carrying heme proteins found in the saliva of a bloodsucking insect from tropical Central and South America, Rhodnius prolixus, the “kissing bug”. NO is kept stable for long periods of time by binding it as an axial ligand to a ferriheme center. The fact that the...

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Bibliografski detalji
Glavni autori: Berry, Robert E., Shokhirev, Maxim N., Ho, Arthur Y. W., Yang, Fei, Shokhireva, Tatiana K., Zhang, Hongjun, Weichsel, Andrzej, Montfort, William R., Walker, F. Ann
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647857/
https://ncbi.nlm.nih.gov/pubmed/19175316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja808105d
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