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Ultraconservation identifies a small subset of extremely constrained developmental enhancers
Extended perfect human-rodent sequence identity of at least 200 base pairs (ultraconservation) is potentially indicative of evolutionary or functional uniqueness. We used a transgenic mouse assay to compare the embryonic enhancer activity of 231 noncoding ultraconserved human genome regions with tha...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2647775/ https://ncbi.nlm.nih.gov/pubmed/18176564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2007.55 |
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