Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

The Hsc/Hsp70 co-chaperones of the BAG (Bcl-2-associated athanogene) protein family are modulators of protein quality control. We examined the specific roles of BAG1 and BAG3 in protein degradation during the aging process. We show that BAG1 and BAG3 regulate proteasomal and macroautophagic pathways...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Gamerdinger, Martin, Hajieva, Parvana, Kaya, A Murat, Wolfrum, Uwe, Hartl, F Ulrich, Behl, Christian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2009
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647772/
https://ncbi.nlm.nih.gov/pubmed/19229298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.29
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