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BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins

Increasing evidence indicates the existence of selective autophagy pathways, but the manner in which substrates are recognized and targeted to the autophagy system is poorly understood. One strategy is transport of a particular substrate to the aggresome, a perinuclear compartment with high autophag...

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Detalhes bibliográficos
Main Authors: Gamerdinger, Martin, Kaya, A Murat, Wolfrum, Uwe, Clement, Albrecht M, Behl, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049430/
https://ncbi.nlm.nih.gov/pubmed/21252941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.203
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