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BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins
Increasing evidence indicates the existence of selective autophagy pathways, but the manner in which substrates are recognized and targeted to the autophagy system is poorly understood. One strategy is transport of a particular substrate to the aggresome, a perinuclear compartment with high autophag...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049430/ https://ncbi.nlm.nih.gov/pubmed/21252941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.203 |
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