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Snail1 controls bone mass by regulating Runx2 and VDR expression during osteoblast differentiation

Bone undergoes continuous remodelling throughout adult life, and the equilibrium between bone formation by osteoblasts and bone resorption by osteoclasts defines the final bone mass. Here we show that Snail1 regulates this balance by controlling osteoblast differentiation. Snail1 is necessary for th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: de Frutos, Cristina A, Dacquin, Romain, Vega, Sonia, Jurdic, Pierre, Machuca-Gayet, Irma, Angela Nieto, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647771/
https://ncbi.nlm.nih.gov/pubmed/19197242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.23
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