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Snail1 controls bone mass by regulating Runx2 and VDR expression during osteoblast differentiation
Bone undergoes continuous remodelling throughout adult life, and the equilibrium between bone formation by osteoblasts and bone resorption by osteoclasts defines the final bone mass. Here we show that Snail1 regulates this balance by controlling osteoblast differentiation. Snail1 is necessary for th...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2647771/ https://ncbi.nlm.nih.gov/pubmed/19197242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.23 |
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