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Snail1 controls bone mass by regulating Runx2 and VDR expression during osteoblast differentiation

Bone undergoes continuous remodelling throughout adult life, and the equilibrium between bone formation by osteoblasts and bone resorption by osteoclasts defines the final bone mass. Here we show that Snail1 regulates this balance by controlling osteoblast differentiation. Snail1 is necessary for th...

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Main Authors: de Frutos, Cristina A, Dacquin, Romain, Vega, Sonia, Jurdic, Pierre, Machuca-Gayet, Irma, Angela Nieto, M
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647771/
https://ncbi.nlm.nih.gov/pubmed/19197242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.23
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