Association studies between the plasmin genes and late-onset Alzhemier’s disease

The plasmin system is involved in the degradation of Aβ peptides, the accumulation of which in brain is a hallmark of Alzheimer’s disease (AD). In a North European case-control AD dataset we studied 14 common variations in the PLG, PAI-1, PLAT and PLI genes encoding components of the plasmin system....

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Hauptverfasser: Shibata, Nobuto, Kawarai, Toshitaka, Meng, Yan, Lee, Joseph H., Lee, Hye-Seung, Wakutani, Yosuke, Shibata, Eri, Pathan, Nazia, Bi, Andrew, Sato, Christine, Sorbi, Sandro, Bruni, Amalia C., Duara, Ranjan, Mayeux, Richard, Farrer, Lindsay A., St George-Hyslop, Peter, Rogaeva, Ekaterina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647723/
https://ncbi.nlm.nih.gov/pubmed/16828203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2006.05.028
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