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Rational design of minimal hypoxia-inducible enhancers
The hypoxia-inducible factor (HIF) activates transcription via binding to the highly variable hypoxia-responsive elements (HREs). All hypoxia-inducible constructs described to date utilize multimers of naturally occurring HREs. Here, we describe the rational design of minimal hypoxia-inducible enhan...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2647722/ https://ncbi.nlm.nih.gov/pubmed/18402769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.03.147 |
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