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Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases

Bcl2 phosphorylation at Ser-70 may be required for the full and potent suppression of apoptosis in IL-3-dependent myeloid cells and can result from agonist activation of mitochondrial protein kinase C (PKC). Paradoxically, expression of exogenous Bcl2 can protect parental cells from apoptosis induce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Deng, Xingming, Ruvolo, Peter, Carr, Boyd, May, W. Stratford
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC26477/
https://ncbi.nlm.nih.gov/pubmed/10677502
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