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Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate

Specification of endothelial cell (EC) fate during vascular development is controlled by distinct key regulators. While Notch plays an essential role in induction of arterial phenotypes, COUP-TFII is required to maintain the venous EC identity. Homeodomain transcription factor Prox1 functions to rep...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Sunju, Kang, Jinjoo, Yoo, Jaehyuk, Ganesan, Sathish K., Cook, Sarah C., Aguilar, Berenice, Ramu, Swapnika, Lee, Juneyong, Hong, Young-Kwon
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647678/
https://ncbi.nlm.nih.gov/pubmed/18815287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-145789
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