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Use of Lung Imaging Studies as Outcome Measures for Development of New Therapies in Cystic Fibrosis
Most cystic fibrosis (CF) drug development has been based upon functional outcomes (e.g., FEV(1)) rather than structural changes. This functional approach has the limitation of being insensitive of early changes in lung disease. Computer tomography (CT) scanning affords the opportunity to establish...
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Thoracic Society
2007
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2647600/ https://ncbi.nlm.nih.gov/pubmed/17652502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.200611-183HT |
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