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Use of Lung Imaging Studies as Outcome Measures for Development of New Therapies in Cystic Fibrosis

Most cystic fibrosis (CF) drug development has been based upon functional outcomes (e.g., FEV(1)) rather than structural changes. This functional approach has the limitation of being insensitive of early changes in lung disease. Computer tomography (CT) scanning affords the opportunity to establish...

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Detalhes bibliográficos
Autor principal: Ramsey, Bonnie W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647600/
https://ncbi.nlm.nih.gov/pubmed/17652502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.200611-183HT
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