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Reduction of the secretory response to Escherichia coli heat-stable enterotoxin by thiol and disulfide compounds.

We examined the effects of disulfide and thiol compounds on Escherichia coli heat-stable enterotoxin (ST) and cyclic GMP-induced secretion. Both cystamine and cystine (disulfide compounds) reduced the secretory responses to submaximal doses of ST in suckling mice (at 0.5 mumol per mouse) and reduced...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Greenberg, R N, Dunn, J A, Guerrant, R L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC264759/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6134677/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.41.1.174-180.1983
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