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Reduction of the secretory response to Escherichia coli heat-stable enterotoxin by thiol and disulfide compounds.

We examined the effects of disulfide and thiol compounds on Escherichia coli heat-stable enterotoxin (ST) and cyclic GMP-induced secretion. Both cystamine and cystine (disulfide compounds) reduced the secretory responses to submaximal doses of ST in suckling mice (at 0.5 mumol per mouse) and reduced...

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Detalhes bibliográficos
Main Authors: Greenberg, R N, Dunn, J A, Guerrant, R L
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC264759/
https://ncbi.nlm.nih.gov/pubmed/6134677
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