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A Novel Mode of Translocation for Cytolethal Distending Toxin

Thermal instability in the toxin catalytic subunit may be a common property of toxins that exit the endoplasmic reticulum (ER) by exploiting the mechanism of ER-associated degradation (ERAD). The Haemophilus ducreyi cytolethal distending toxin (HdCDT) does not utilize ERAD to exit the ER, so we pred...

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Autors principals: Guerra, Lina, Nemec, Kathleen N., Massey, Shane, Tatulian, Suren A., Thelestam, Monica, Frisan, Teresa, Teter, Ken
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647582/
https://ncbi.nlm.nih.gov/pubmed/19118582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2008.11.017
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