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O-Phospho-L-serine and the Thiocarboxylated Sulfur Carrier Protein CysO-COSH are Substrates for CysM, a Cysteine Synthase from Mycobacterium tuberculosis

The kinetic pathway of CysM, a cysteine synthase from Mycobacterium tuberculosis, the expression of which is upregulated under conditions of oxidative stress, was studied by transient-state kinetic techniques. This enzyme exhibits extensive homology with the B-isozymes of the well-studied O-acetylse...

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Detalhes bibliográficos
Main Authors: O’Leary, Seán E., Jurgenson, Christopher T., Ealick, Steven E., Begley, Tadhg P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647513/
https://ncbi.nlm.nih.gov/pubmed/18842002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8013664
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