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A designed protein as experimental model of primordial folding
How do proteins accomplish folding during early evolution? Theoretically the mechanism involves the selective stabilization of the native structure against all other competing compact conformations in a process that involves cumulative changes in the amino acid sequence along geological timescales....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2647338/ https://ncbi.nlm.nih.gov/pubmed/19240216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812108106 |
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