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Ultrafast folding kinetics of WW domains reveal how the amino acid sequence determines the speed limit to protein folding
Protein (un)folding rates depend on the free-energy barrier separating the native and unfolded states and a prefactor term, which sets the timescale for crossing such barrier or folding speed limit. Because extricating these two factors is usually unfeasible, it has been common to assume a constant...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6486773/ https://ncbi.nlm.nih.gov/pubmed/30967507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1900203116 |
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