Replication at body temperature selects a neurovirulent herpes simplex virus type 2.

A prototype strain of herpes simplex virus type 2 (HG-52) replicated at 31 degrees C was avirulent when inoculated intracranially into mice. This property was not altered after serial passage of the agent at 31 degrees C, but the virus became virulent after passage at 37.5 degrees C. The selection w...

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Detaylı Bibliyografya
Yayımlandı:Infect Immun
Asıl Yazarlar: Thompson, R L, Stevens, J G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1983
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC264722/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6307887/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.41.2.855-857.1983
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