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RNA-mediated epigenetic programming of a genome-rearrangement pathway

Genome-wide DNA rearrangements occur in many eukaryotes but are most exaggerated in ciliates, making them ideal model systems for epigenetic phenomena. During development of the somatic macronucleus, Oxytricha trifallax destroys 95% of its germ line, severely fragmenting its chromosomes, and then un...

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Detalhes bibliográficos
Main Authors: Nowacki, Mariusz, Vijayan, Vikram, Zhou, Yi, Schotanus, Klaas, Doak, Thomas G., Landweber, Laura F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647009/
https://ncbi.nlm.nih.gov/pubmed/18046331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06452
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