Loading...

RNA-mediated epigenetic programming of a genome-rearrangement pathway

Genome-wide DNA rearrangements occur in many eukaryotes but are most exaggerated in ciliates, making them ideal model systems for epigenetic phenomena. During development of the somatic macronucleus, Oxytricha trifallax destroys 95% of its germ line, severely fragmenting its chromosomes, and then un...

Full description

Saved in:
Bibliographic Details
Main Authors: Nowacki, Mariusz, Vijayan, Vikram, Zhou, Yi, Schotanus, Klaas, Doak, Thomas G., Landweber, Laura F.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647009/
https://ncbi.nlm.nih.gov/pubmed/18046331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06452
Tags: Add Tag
No Tags, Be the first to tag this record!